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Psilocybin, found naturally in more than 200 species of mushrooms, has a long history of use by humans. Called “flesh of the gods” by the Aztecs, the mushrooms were widely consumed in religious ceremonies by pre-contact indigenous cultures throughout the Americas. Cave paintings in Spain and Algeria suggest ritualized ingestion dating back as far as 9,000 years. Brutally suppressed by Christian authorities on both sides of the Atlantic, indigenous psilocybin use was nearly eradicated until the late 195o’s when Western psychiatry rediscovered it.

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